Avandia manufacturers, GlaxoSmithKline, recently receive U.S. Food and Drug Administration (FDA) warnings after the FDA uncovered information on the type 2 diabetes drug to have been withheld by the company.Rosiglitazone maleate is the generic name of Avandia, which is taken orally to control insulin levels in the body. The New England Journal of Medicine released Avandia study results that linked the drug to an increased risk of heart disease, since that time, the drug’s sales have decreased and it is no longer the best-selling diabetic drug, as news reports once stated.The report, released in May 2007, found that patients were more likely to suffer from heart disease after taking Avandia for a period of time and individuals with a history of heart disease were likely to suffer a worse outcome, as the drug increased the ill-effects of heart disease among patients and resulted in death from cardiovascular-related causes. In fact, the study found a 43 percent increased risk of myocardial infarction, otherwise known as a heart attack. After the May 2007 reports of Avandia increasing the risk of heart disease, the drug has seen a decline in sales and both regulators in the U.S. market and European market have increased […]
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Charcot’s foot is a condition that is often identified with diabetes, is used to describe the effect of bone softening that happens within the foot internally. It is a complication that occurs when one loses the ability to feel or sense pain. This occurs as a result of neuropathy or extreme nerve damage. The bones become too weak and eventually become easily fractured. Because the nerves have become too damaged, stimuli are no longer being transmitted such as feelings of pain. In addition, muscle movement is also hampered. Since nothing is felt within the area due to nerve damage, the whole bone structure of the feet experience stress and trauma repeatedly until it collapses one day.As the person continues to use his or her feet for walking despite the condition, the foot begins to change its shape. In its developed stage, the arch of the foot will probably collapse, therefore giving the foot a rocker-bottom shape. Due to that reason, even normal walking can become very painful and difficult.Charcot foot is a very serious degenerative condition which can lead to disability and if not treated immediately, can result to foot amputation.Charcot’s foot is highly prone to patients with diabetes. This […]
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